Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039915 | 0.80 | ALDH1A1 (0.44) | POLBHPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28039858 | 0.76 | HPGD (0.45) | POLBHPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28823518 | 0.76 | L3MBTL1 (0.45) | POLBHPGDTSHRALDH1A1MAPK1 | |
| SCHEMBL28039872 | 0.72 | ALDH1A1 (0.33) | POLBHPGDTSHRALDH1A1ALOX12 | |
| SCHEMBL16098213 | 0.70 | ALDH1A1 (0.34) | POLBHPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31550805 | 0.67 | ADORA3 (0.40) | POLBHPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31550786 | 0.65 | ADORA3 (0.39) | POLBHPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16096245 | 0.63 | POLB (0.34) | POLBHPGDALDH1A1ALOX12NPSR1 | |
| SCHEMBL28040302 | 0.63 | NPC1 (0.43) | HPGDCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2730002 | 0.63 | SMN1; SMN2 (0.47) | POLBHPGDCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |