Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.54 |
| ▸ | TUBB | P07437 | 2/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31157848 | 0.84 | CYP19A1 (0.77) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL16641094 | 0.84 | CYP19A1 (0.77) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL20696534 | 0.83 | TUBB4A (0.74) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL29689431 | 0.83 | TUBB4A (0.74) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL10335393 | 0.82 | CYP19A1 (0.81) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL29406655 | 0.78 | AKR1B1 (0.74) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL28040069 | 0.78 | CALM1 (0.78) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL30869991 | 0.77 | ATM (0.70) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL10343404 | 0.77 | ATM (0.70) | CYP19A1ATMKDM4ECA2POLB | |
| SCHEMBL7436339 | 0.76 | TUBB4A (0.76) | CYP19A1ATMKDM4ECA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | claimed |
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | disclosed |