Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 4/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28040923 | 0.89 | ELANE (0.37) | ELANEKDM4EALDH1A1SMN1; SMN2MAPT | |
| Ethoxycarbonyl Group SCHEMBL28801419 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL8404385 | 0.82 | ADORA3 (0.44) | ELANEKDM4EALDH1A1MAPTMAPK1 | |
| Ethoxycarbonyl Group SCHEMBL28828682 | 0.74 | DRD4 (0.34) | ELANEKDM4EALDH1A1MAPTCYP1A2 | |
| Ethoxycarbonyl Group SCHEMBL28040925 | 0.73 | TDP1 (0.39) | KDM4EALDH1A1SMN1; SMN2MAPTMAPK1 | |
| Ethoxycarbonyl Group SCHEMBL28040931 | 0.73 | TDP1 (0.39) | KDM4EALDH1A1SMN1; SMN2MAPTMAPK1 | |
| Ethoxycarbonyl Group SCHEMBL28040584 | 0.73 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27437611 | 0.71 | MEN1 (0.43) | KDM4EALDH1A1SMN1; SMN2MAPTMAPK1 | |
| Ethoxycarbonyl Group SCHEMBL27894122 | 0.71 | TSHR (0.39) | KDM4EALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL20212713 | 0.71 | ALDH1A1 (0.38) | KDM4EALDH1A1RAB9ACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770435-B | Pyrazolopyrimidines and the purposes as PDE10 inhibitor thereof | MITSUBISHI TANABE PHARMA CORP. (JP) | 2015-11-25 | — | — | CN | disclosed |