Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169977 | 0.73 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL92396 | 0.73 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL239179 | 0.73 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL63526 | 0.73 | ESR1 (0.70) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL439492 | 0.73 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL28415835 | 0.71 | ESR1 (0.46) | ESR1ESR2NR1H2NR1H3TSHR | |
| Phosphine SCHEMBL28991719 | 0.71 | ESR1 (0.46) | ESR1ESR2NR1H2NR1H3TSHR | |
| Methane SCHEMBL28815257 | 0.71 | ESR1 (0.46) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL12191039 | 0.71 | ESR1 (0.75) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL7768857 | 0.71 | ESR1 (0.46) | ESR1ESR2NR1H2NR1H3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418567-B | The production method of beraprost | 琅歌生物技术股份有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-105315247-B | The production method of beraprost | 琅歌生物技术股份有限公司 | 2019-07-26 | — | — | CN | disclosed |
| CN-107406468-A | Silicone-modified photoinitiators and photocurable adhesive compositions thereof | 汉高股份有限及两合公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-105418567-A | METHOD OF PRODUCING BERAPROST | Lung LLC | 2016-03-23 | — | — | CN | disclosed |
| CN-105315247-A | METHOD OF PRODUCING BERAPROST | Lung LLC | 2016-02-10 | — | — | CN | disclosed |
| CN-103717585-B | Method for producing beraprost | LUNG BIOTECHNOLOGY PBC (US) | 2015-11-25 | — | — | CN | disclosed |