SCHEMBL439492

SCHEMBL439492

C[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
NR1H2 P55055 2/20 0.41
NR1H3 Q13133 2/20 0.41
TSHR P16473 4/20 0.39
ACHE P22303 2/20 0.39
LMNA P02545 1/20 0.39
ALOX12 P18054 1/20 0.39
BBOX1 O75936 1/20 0.37
EHMT2 Q96KQ7 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 4/20 0.36
CCR1 P32246 1/20 0.36
CCR8 P51685 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.35
NPC1 O15118 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12124325 0.86 ACHE (0.50) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL12124343 0.86 ACHE (0.50) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL15863526 0.84 ESR1 (0.38) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL22888814 0.84 ESR1 (0.74) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL12014944 0.84 ALDH1A1 (0.48) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL28589125 0.84 TSHR (0.48) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL388105 0.84 ALDH1A1 (0.48) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL23532322 0.82 ALDH1A1 (0.50) ESR1ESR2MAPTRAB9AMEN1
SCHEMBL22198379 0.82 ESR1 (0.58) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL20156757 0.82 ESR1 (0.41) ESR1ESR2NR1H2NR1H3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 754 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955549-A Method for dehydrogenating and coupling silicon and aromatic heterocyclic compound and application thereof 中山大学 2024-11-15 CN claimed
CN-115820207-A Lignin-based silicon gel and preparation method thereof, application of lignin-based silicon gel in IGBT and IGBT packaging structure 重庆云潼科技有限公司 2023-03-21 CN claimed
US-20210121863-A1 Catalyst Systems Including Salan Catalyst and Non-Coordinating Anion Type Activator Containing Cation Having Alkyl Groups and uses Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2021-04-29 US claimed
CN-111701284-B Defoaming agent and preparation method and application thereof 山东佑震化工有限公司 2021-04-20 CN claimed
CN-111701284-A Defoaming agent and preparation method and application thereof 山东佑震化工有限公司 2020-09-25 CN claimed
US-20200112057-A1 ALKALI ION CONDUCTING PLASTIC CRYSTALS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-04-09 US claimed
US-20190020060-A1 ALKALI ION CONDUCTING PLASTIC CRYSTALS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2019-01-17 US claimed
CN-108948412-A A kind of siliceous poromeric preparation method for supercapacitor 齐鲁工业大学 2018-12-07 CN claimed
CN-107759796-A The preparation method of a kind of porous super cross-linked polymer 齐鲁工业大学 2018-03-06 CN claimed
EP-2699949-B1 LIQUID FORMULATION FOR OPHTHALMIC DEVICES PARROT DRONES (FR) 2017-12-06 EP claimed
US-20030039825-A1 Heat exchanging DUVALL JAMES H (US) 2003-02-27 US claimed
US-20020163093-A1 Controlled atmosphere sintering process for urania containing silica additive GENERAL ELECTRIC COMPANY 2002-11-07 US claimed
US-6391442-B1 ELASTOMER; WAX OR WAXLIKE MELTING POINT MODIFIER; THERMALLY CONDUCTIVE FILLER; HEAT TRANSFER AGENT; MICROPROCESSOR POWER ASSEMBLY; HEAT SINK SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2002-05-21 US claimed
US-20020033545-A1 Controlled atmosphere sintering process for urania containing silica additive GENERAL ELECTRIC COMPANY 2002-03-21 US claimed
US-6190582-B1 Controlled atmosphere sintering process for urania containing silica additive GENERAL ELECTRIC COMPANY 2001-02-20 US claimed
EP-1067164-A1 Phase change thermal interface material Saint-Gobain Performance Plastics Corporation (US) 2001-01-10 EP claimed
US-5946364-A Densification test procedure for urania GENERAL ELECTRIC COMPANY (US) 1999-08-31 US claimed
EP-0614916-B1 Process for producing polyolefin IDEMITSU PETROCHEMICAL CO (JP) 1998-10-07 EP claimed
US-5605990-A USING CATALYST COMPRISING TITANIUM COMPOUND, ALUMINOXANE, AROMATIC RING-CONTAINING COMPOUND IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-02-25 US claimed
EP-0614916-A1 Process for producing polyolefin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-14 EP claimed