Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464684 | 0.85 | SMN1; SMN2 (0.43) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL7462737 | 0.83 | RAB9A (0.49) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL12678495 | 0.83 | RAB9A (0.56) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL7453612 | 0.81 | NPC1 (0.51) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL5120910 | 0.79 | SMN1; SMN2 (0.44) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL14668531 | 0.79 | RAB9A (0.48) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL7453984 | 0.77 | SMN1; SMN2 (0.47) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL955246 | 0.77 | PSIP1 (0.47) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL10413567 | 0.77 | SMN1; SMN2 (0.43) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 | |
| SCHEMBL31402193 | 0.77 | SMN1; SMN2 (0.47) | RAB9ANPC1KDM4EGALR3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459258-B | Preparation and use of 1,2, 4-triazolo [1,5a ] pyridine derivatives | CEPHALON, INC. (US) | 2015-11-25 | — | — | CN | disclosed |