Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1291337 | 0.82 | ALDH1A1 (0.47) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL14668531 | 0.82 | RAB9A (0.48) | CA2MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5120910 | 0.82 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL9464684 | 0.80 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL31402193 | 0.80 | SMN1; SMN2 (0.47) | CA1CA2CA12CA4CA6 | |
| SCHEMBL10413567 | 0.80 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL7453984 | 0.80 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11617729 | 0.79 | SMN1; SMN2 (0.50) | CA1CA2CA12CA4CA9 | |
| SCHEMBL27778615 | 0.79 | PSIP1 (0.43) | PSIP1CA1CA2CA12CA4 | |
| SCHEMBL12678495 | 0.78 | RAB9A (0.56) | CA2MAPTSMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729089-B2 | Pyrido(3,2-d)pyrimidines useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2014-05-20 | — | — | US | claimed |
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-31 | — | — | US | claimed |
| CN-104583255-B | Antifouling paint compositions | PPG涂料欧洲有限责任公司 | 2017-11-14 | — | — | CN | disclosed |
| CN-106795381-A | Erodible antifouling paint composition | PPG涂料欧洲有限责任公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106133027-A | Coating composition | PPG涂料欧洲有限责任公司 | 2016-11-16 | — | — | CN | disclosed |
| EP-1845973-B1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LTD (GB) | 2015-08-12 | — | — | EP | disclosed |
| US-9051278-B2 | 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators | ASTEX THERAPEUTICS, LTD. (GB) | 2015-06-09 | — | — | US | disclosed |
| EP-2256106-B1 | 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinases (CDK) and glycogen synthase kinase-3 (GSK-3) modulators | ASTEX THERAPEUTICS LTD (GB) | 2015-05-06 | — | — | EP | disclosed |
| CN-104583255-A | Antifouling coating composition | PPG COATINGS EUROP B V | 2015-04-29 | — | — | CN | disclosed |
| US-20140371213-A1 | 3,4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASE AND GLYCOGEN SYNTHASE KINASE-3 MODULATORS | ASTEX THERAPEUTICS, LTD. (GB) | 2014-12-18 | — | — | US | disclosed |
| US-8779147-B2 | 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators | ASTEX THERAPEUTICS, LTD. (GB) | 2014-07-15 | — | — | US | disclosed |
| CN-1784478-A | Silyl esters, their use in binder systems and coating compositions and process for their production | SIGMAKALON B V (NL) | 2006-06-07 | — | — | CN | disclosed |
| EP-1651612-A1 | 3,4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASES (CDK) AND GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MODULATORS | Astex Therapeutics Limited (GB) | 2006-05-03 | — | — | EP | disclosed |
| CN-1618905-A | Improved marine paint compositions | SIGMA COATINGS BV (NL) | 2005-05-25 | — | — | CN | disclosed |
| WO-2005012256-A1 | 3, 4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASES (CDK) AND GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |
| CN-1578816-A | Paint compositions comprising esters of rosin and methods for producing the same | SIGMA COATINGS BV (NL) | 2005-02-09 | — | — | CN | disclosed |
| CN-1549832-A | Binders with low content in hydrolysable monomer suitable for self-polishing antifouling paints | 西格马涂料有限公司 | 2004-11-24 | — | — | CN | disclosed |
| CN-1174056-C | Improved marine paint composition | — | 2004-11-03 | — | — | CN | disclosed |
| CN-1418228-A | Metal-free binders for self-polishing antifouling paints | SIGMA COATINGS BV (NL) | 2003-05-14 | — | — | CN | disclosed |
| CN-1418244-A | Improved marine paint composition | SIGMA COATINGS BV (NL) | 2003-05-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371213-A1 | 3,4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASE AND GLYCOGEN SYNTHASE KINASE-3 MODULATORS | CDK1, CDK3, CDK13 | PSIP1 2424/4885CA1 1079/4885CA2 1443/4885 |
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | PNPO, DPYD, PNP | PSIP1 1173/4885CA1 4802/4885CA2 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.