Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105495 | 0.84 | IDO1 (0.50) | CYP17A1CYP21A2CYP11B1TAAR1 | |
| SCHEMBL8591746 | 0.83 | TAAR1 (0.65) | MAOAMAOBALDH1A1TAAR1 | |
| Benzyl Alcohol SCHEMBL28019915 | 0.82 | TSHR (0.52) | MAOAALOX15TDP1HTR2ASMN1; SMN2 | |
| SCHEMBL4648373 | 0.81 | ALDH1A1 (0.58) | MAOAMAOBALDH1A1HPGDALOX15 | |
| SCHEMBL28019913 | 0.80 | TSHR (0.54) | MAOATDP1HTR2AL3MBTL1 | |
| SCHEMBL25978995 | 0.80 | CALM1 (0.60) | TAAR1 | |
| SCHEMBL654154 | 0.79 | TAAR1 (0.56) | MAOAMAOBALDH1A1HPGDALOX15 | |
| SCHEMBL7733392 | 0.78 | HTR2A (0.48) | MAOAMAOBALDH1A1HPGDALOX15 | |
| SCHEMBL62125 | 0.78 | ALDH1A1 (0.69) | MAOAMAOBALDH1A1HPGDALOX15 | |
| SCHEMBL9741303 | 0.78 | ALDH1A1 (0.69) | MAOAMAOBALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104995176-A | Hydantoins that modulate BACE mediated APP processing | BUCK INST FOR RES ON AGING | 2015-10-21 | — | — | CN | disclosed |