Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105773 | 0.84 | CES2 (0.39) | TAAR1MAOBALDH1A1HPGD | |
| SCHEMBL7050507 | 0.82 | HTR2A (0.44) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL16191225 | 0.79 | HTT (0.51) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL4648373 | 0.79 | ALDH1A1 (0.58) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL7052561 | 0.79 | HTR2A (0.44) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL28041238 | 0.78 | MAOA (0.46) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL7734826 | 0.77 | LTA4H (0.61) | TAAR1ALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL23913833 | 0.77 | KCNH2 (0.41) | TAAR1MAOBTDP1KCNH2L3MBTL1 | |
| SCHEMBL62125 | 0.76 | ALDH1A1 (0.69) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL9741303 | 0.76 | ALDH1A1 (0.69) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |