Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL6150285 | 0.97 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL147794 | 0.97 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28098837 | 0.97 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL6150292 | 0.97 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Pimelic Acid SCHEMBL7457377 | 0.94 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL10906790 | 0.94 | SLC22A6 (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Pimelic Acid SCHEMBL7457359 | 0.94 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5681272 | 0.94 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL10906793 | 0.94 | SLC22A6 (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL10558405 | 0.94 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111422-A | Preparation method for fully-biodegradable copolyester | ANQING HE XING CHEMICAL CORP LTD | 2015-12-02 | — | — | CN | claimed |
| CN-105111422-A | Preparation method for fully-biodegradable copolyester | ANQING HE XING CHEMICAL CORP LTD | 2015-12-02 | — | — | CN | disclosed |