Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL147794 | 1.00 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28098837 | 1.00 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL6150292 | 1.00 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5681272 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Pimelic Acid SCHEMBL7457377 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28041339 | 0.97 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL10558405 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Pimelic Acid SCHEMBL7457359 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5681282 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL29148760 | 0.94 | SLC22A6 (0.69) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109898085-A | It moves back tin combination liquid and moves back tin method | 深圳市松柏实业发展有限公司 | 2019-06-18 | — | — | CN | claimed |
| EP-1594946-A1 | HARD SURFACE CLEANING COMPOSITIONS | Reckitt Benckiser Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004074420-A1 | HARD SURFACE CLEANING COMPOSITIONS | RECKITT BENCKISER INC (US) | 2004-09-02 | — | — | WO | claimed |
| EP-0598037-A1 | BUFFERED FORMULATION OF PEG-SOD | SANOFI (FR) | 1994-05-25 | — | — | EP | claimed |
| EP-0535723-A1 | Buffered formulation of capitals | STERLING WINTHROP INC. (US) | 1993-04-07 | — | — | EP | claimed |
| WO-1993002701-A1 | BUFFERED FORMULATION OF PEG-SOD | STERLING WINTHROP INC. (US) | 1993-02-18 | — | — | WO | claimed |
| US-4769381-A | STORAGE STABILITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1988-09-06 | — | — | US | claimed |
| US-20230165799-A1 | TWIN-SCREW DRY GRANULATION FOR PRODUCING SOLID FORMULATIONS | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2023-06-01 | — | — | US | disclosed |
| US-11529313-B2 | Twin-screw dry granulation for producing solid formulations | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2022-12-20 | — | — | US | disclosed |
| CN-114380977-B | TPU (thermoplastic polyurethane) shoe material and preparation method thereof | 广东康诚新材料科技股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114380977-A | TPU (thermoplastic polyurethane) shoe material and preparation method thereof | 广东康诚新材料科技股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| EP-3445337-B1 | TWIN-SCREW DRY GRANULATION FOR PRODUCING SOLID FORMULATIONS | UNIV MISSISSIPPI (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20200345643-A1 | TWIN-SCREW DRY GRANULATION FOR PRODUCING SOLID FORMULATIONS | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2020-11-05 | — | — | US | disclosed |
| US-10786459-B2 | Twin-screw dry granulation for producing solid formulations | R. P. SCHERER TECHNOLOGIES LLC (US) | 2020-09-29 | — | — | US | disclosed |
| WO-2019181719-A1 | RESIN COMPOSITION FOR TRANSFER PAPER AND MULTILAYER BODY | DIC株式会社 | 2019-09-26 | — | — | WO | disclosed |
| CN-109898085-A | It moves back tin combination liquid and moves back tin method | 深圳市松柏实业发展有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109749018-A | A kind of grafted polyester polyalcohol and preparation method thereof | 上海汇得科技股份有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-105622911-B | A kind of unsaturated aliphatic aromatic series polylactic-acid block copolymer | 中国科学院长春应用化学研究所 | 2017-11-28 | — | — | CN | disclosed |
| US-20170319486-A1 | TWIN-SCREW DRY GRANULATION FOR PRODUCING SOLID FORMULATIONS | CATALENT PHARMA SOLUTIONS INC. (US) | 2017-11-09 | — | — | US | disclosed |
| WO-2017185040-A1 | TWIN-SCREW DRY GRANULATION FOR PRODUCING SOLID FORMULATIONS | UNIVERSITY OF MISSISSIPPI (US) | 2017-10-26 | — | — | WO | disclosed |