Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL27638226 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL2142111 | 0.88 | NPC1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6674992 | 0.86 | CYP19A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL27794748 | 0.84 | ACHE (0.33) | — | |
| Hydrochloric Acid SCHEMBL2805246 | 0.82 | — | — | |
| SCHEMBL6303309 | 0.77 | — | — | |
| SCHEMBL4811799 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28371794 | 0.74 | — | — | |
| SCHEMBL6250606 | 0.73 | — | — | |
| SCHEMBL6053802 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770265-A | Catalyst system and method of use thereof | 埃克森美孚化学专利公司 | 2020-02-07 | — | — | CN | claimed |
| CN-110770265-A | Catalyst system and method of use thereof | 埃克森美孚化学专利公司 | 2020-02-07 | — | — | CN | disclosed |
| US-10457786-B2 | Biaxially-stretched film and ethylene polymer composition | PRIME POLYMER CO., LTD. (JP) | 2019-10-29 | — | — | US | disclosed |
| CN-105294779-A | Crosslinked metallocene compound, catalyst for olefin polymerization using same, and ethylene polymer obtained using said catalyst | PRIME POLYMER CO LTD | 2016-02-03 | — | — | CN | disclosed |
| CN-105008439-A | Biaxially stretched film, and ethylene-type polymer composition | PRIME POLYMER CO LTD | 2015-10-28 | — | — | CN | disclosed |
| CN-104024326-A | Ethylene polymer composition and molded body obtained therefrom | MITSU CHEMICALS INC | 2014-09-03 | — | — | CN | disclosed |
| US-8785574-B2 | Bridged metallocene compound, olefin polymerization catalyst containing the same, and ethylene polymer obtained with the catalyst | MITSUI CHEMICALS, INC. (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20140114031-A1 | BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST | PRIME POLYMER CO., LTD. (JP) | 2014-04-24 | — | — | US | disclosed |
| US-20100292421-A1 | BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST | MITSUI CHEMICALS, INC. | 2010-11-18 | — | — | US | disclosed |
| CN-101868471-A | Crosslinked metallocene compound, catalyst for olefin polymerization using same, and ethylene polymer obtained using said catalyst | PRIME POLYMER CO LTD | 2010-10-20 | — | — | CN | disclosed |
| CN-1184242-C | Catalyst systems and their use in polymerization process | UNIVATION TECH LLC (US) | 2005-01-12 | — | — | CN | disclosed |
| US-6492472-B2 | MELT PROCESSABILITY; COORDINATION CATALYST | UNIVATION TECHNOLOGIES, LLC | 2002-12-10 | — | — | US | disclosed |
| CN-1382162-A | Catalyst systems and their use in polymerization process | UNIVATION TECHNOLOIGES LLC (US) | 2002-11-27 | — | — | CN | disclosed |
| US-20020010077-A1 | Mixed catalysts and their use in a polymerization process | LUE CHING-TAI (US) | 2002-01-24 | — | — | US | disclosed |
| US-6207606-B1 | AT LEAST ONE BRIDGED, BULKY LIGAND METALLOCENE-TYPE COMPOUND, AND AT LEAST ONE BRIDGED, ASYMMETRICALLY SUBSTITUTED, BULKY LIGAND METALLOCENE-TYPE COMPOUND | UNIVATION TECHNOLOGIES, LLC | 2001-03-27 | — | — | US | disclosed |
| EP-1084153-A1 | MIXED CATALYSTS AND THEIR USE IN A POLYMERIZATION PROCESS | Univation Technologies LLC (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999060032-A1 | MIXED CATALYSTS AND THEIR USE IN A POLYMERIZATION PROCESS | UNIVATION TECHNOLOGIES LLC (US) | 1999-11-25 | — | — | WO | disclosed |