SCHEMBL28041486

SCHEMBL28041486

C=C[Si](OC)(OC)OC.O=P(O)(O)C=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
KDM4E B2RXH2 3/20 0.37
LMNA P02545 3/20 0.37
POLB P06746 2/20 0.37
HTT P42858 1/20 0.37
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
TRPA1 O75762 1/20 0.35
GLA P06280 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP2C19 P33261 2/20 0.34
CMA1 P23946 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
HSD17B10 Q99714 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041485 0.82 ALDH1A1 (0.33) MAPTKDM4ELMNAPOLBMEN1
SCHEMBL8712443 0.80 TSHR (0.48) MAPTLMNAMAPK1ALOX15TSHR
SCHEMBL233260 0.80 HDAC1 (0.48) MAPTLMNAMAPK1ALOX15TSHR
SCHEMBL541471 0.80 HDAC1 (0.48) MAPTLMNAMAPK1ALOX15TSHR
Styrene SCHEMBL7612533 0.79 ALDH1A1 (0.54) MAPTKDM4ELMNAPOLBHTT
SCHEMBL23405490 0.78 HDAC1 (0.46) MAPTLMNAMAPK1ALOX15TSHR
Water SCHEMBL9439968 0.78 HDAC1 (0.46) MAPTLMNAMAPK1ALOX15TSHR
SCHEMBL23405477 0.78 HDAC1 (0.46) MAPTLMNAMAPK1ALOX15TSHR
SCHEMBL23405502 0.78 HDAC1 (0.46) MAPTLMNAMAPK1ALOX15TSHR
SCHEMBL27406196 0.78 HDAC1 (0.47) MAPTLMNAMAPK1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105206854-B A kind of block copolymerization soda acid type phosphonate group high temperature proton exchange film and preparation method thereof 武汉理工大学 2017-12-29 CN claimed
CN-105206854-A Block copolymerization acid-base phosphonic acid group high-temperature proton exchange membrane and preparation method thereof UNIV WUHAN TECH 2015-12-30 CN claimed
CN-105206854-B A kind of block copolymerization soda acid type phosphonate group high temperature proton exchange film and preparation method thereof 武汉理工大学 2017-12-29 CN disclosed
CN-105206854-B A kind of block copolymerization soda acid type phosphonate group high temperature proton exchange film and preparation method thereof 武汉理工大学 2017-12-29 CN disclosed
CN-105206854-A Block copolymerization acid-base phosphonic acid group high-temperature proton exchange membrane and preparation method thereof UNIV WUHAN TECH 2015-12-30 CN disclosed