Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342739 | 0.90 | NOTUM (1.00) | NOTUMMAPTF2KMT2AKCNJ1 | |
| SCHEMBL28994295 | 0.88 | NOTUM (0.95) | NOTUMMAPTF2KMT2AKCNJ1 | |
| SCHEMBL3962509 | 0.88 | NOTUM (0.95) | NOTUMMAPTF2KMT2AKCNJ1 | |
| Hydrochloric Acid SCHEMBL2897369 | 0.88 | NOTUM (0.95) | NOTUMMAPTF2KMT2AKCNJ1 | |
| SCHEMBL7096356 | 0.88 | NOTUM (0.95) | NOTUMMAPTF2KMT2AKCNJ1 | |
| Bromide SCHEMBL3939883 | 0.88 | NOTUM (0.95) | NOTUMMAPTF2KMT2AKCNJ1 | |
| SCHEMBL1163779 | 0.86 | NOTUM (0.64) | NOTUMMAPTF2KMT2AKCNJ1 | |
| SCHEMBL1353899 | 0.83 | NOTUM (0.60) | NOTUMMAPTF2KMT2ASMN1; SMN2 | |
| SCHEMBL987888 | 0.82 | NOTUM (0.84) | NOTUMMAPTF2KMT2AKCNJ1 | |
| Thiophene SCHEMBL5329358 | 0.79 | NOTUM (0.78) | NOTUMMAPTF2KMT2AKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104086485-B | Prepare the method for poly-substituted quinoline type aromatic ring pyridine derivate | TSINGHUA UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |