SCHEMBL28041895

SCHEMBL28041895

CCNC(=O)CC(=O)C(=O)NCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.44
FAAH O00519 1/20 0.43
PLAAT3 P53816 1/20 0.40
PLAAT5 Q96KN8 1/20 0.40
PLAAT2 Q9NWW9 1/20 0.40
PLAAT4 Q9UL19 1/20 0.40
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5909428 0.80 MCL1 (0.55) MCL1FAAHMMP1MMP2MMP3
SCHEMBL8454947 0.78
SCHEMBL3060269 0.76 MMP1 (0.48) MCL1FAAHPLAAT3PLAAT5PLAAT2
Water SCHEMBL18153612 0.76 PLAAT3 (0.41) MCL1FAAHPLAAT3PLAAT5PLAAT2
SCHEMBL4529642 0.75
SCHEMBL28886374 0.75 MCL1 (0.50) MCL1FAAHMMP1MMP2MMP3
SCHEMBL15144386 0.74 CES2 (0.55) FAAHPLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL7784191 0.72
SCHEMBL649664 0.72
SCHEMBL6582098 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105246473-A Fe(iii) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemia VIFOR INT AG 2016-01-13 CN disclosed