Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407349 | 0.89 | ADRB1 (0.53) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL1361268 | 0.85 | ADRB1 (0.58) | ADRB1ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL11067105 | 0.84 | ADRB1 (0.74) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL21855628 | 0.82 | RECQL (0.50) | ADRB1ALDH1A1NPSR1ALOX15GAA | |
| SCHEMBL23843550 | 0.80 | ADRB1 (0.69) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL29058159 | 0.80 | ADRB1 (0.69) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL9065218 | 0.79 | LMNA (0.68) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL30228454 | 0.79 | LMNA (0.68) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL8894088 | 0.79 | LMNA (0.68) | ADRB1ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL19640696 | 0.78 | MAPT (0.51) | ALDH1A1MAPK1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288824-B | Tetrahydropyridine Pyridione derivatives, its preparation method and application | SHANGHAI NORMAL UNIVERSITY (CN) | 2015-12-09 | — | — | CN | disclosed |