Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 6/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.47 |
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251120 | 0.98 | BHMT (0.59) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL28251214 | 0.93 | BHMT (0.60) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL5285668 | 0.93 | BHMT (0.56) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL2454580 | 0.91 | BHMT (0.59) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL18832141 | 0.89 | BHMT (0.70) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL11575012 | 0.89 | BHMT (0.70) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL18832139 | 0.89 | BHMT (0.70) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL2367837 | 0.89 | BHMT (0.70) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL18832137 | 0.89 | BHMT (0.70) | BHMTGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL2367840 | 0.89 | BHMT (0.70) | BHMTGRIK1GRIK2SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130871-B | A kind of sulfur derivatives and its preparation method and application of pyrrolin ketone | 南京农业大学 | 2018-11-09 | — | — | CN | disclosed |
| CN-105130871-A | Pyrrolidone sulfur derivatives and their preparation method and application | UNIV NANJING AGRICULTURAL | 2015-12-09 | — | — | CN | disclosed |