Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 11/20 | 0.70 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 2/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367837 | 1.00 | BHMT (0.70) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL18832139 | 1.00 | BHMT (0.70) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL2367840 | 1.00 | BHMT (0.70) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL18832141 | 1.00 | BHMT (0.70) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL18832137 | 1.00 | BHMT (0.70) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL18832133 | 0.98 | BHMT (0.69) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL60520 | 0.93 | BHMT (0.66) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL4955426 | 0.93 | BHMT (0.66) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL1285565 | 0.93 | BHMT (0.66) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL28042282 | 0.89 | BHMT (0.60) | BHMTBHMT2NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139635-A | Cysteamine derivatives for oral treatment of seborrhea | L'OREAL (FR) | 1979-02-13 | — | — | US | disclosed |
| US-4035492-A | Oral treatment of seborrhea with cysteamine derivatives | L'OREAL (FR) | 1977-07-12 | — | — | US | disclosed |
| US-3950542-A | Cysteamine derivatives for oral treatment of seborrhea | L'OREAL (FR) | 1976-04-13 | — | — | US | disclosed |