Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042131 | 0.94 | KCNH2 (0.60) | MAPTKCNH2CRHBPCRHR2AR | |
| SCHEMBL629033 | 0.86 | CRHBP (0.59) | KCNH2CRHBPCRHR2MC4RALDH1A1 | |
| SCHEMBL16682369 | 0.85 | KCNH2 (0.67) | KCNH2CRHBPCRHR2MC4RALDH1A1 | |
| SCHEMBL28042132 | 0.85 | CRHBP (0.55) | KCNH2CRHBPCRHR2ARMC4R | |
| SCHEMBL11240200 | 0.83 | KCNH2 (0.71) | MAPTKCNH2ALDH1A1 | |
| SCHEMBL11233725 | 0.83 | KCNH2 (0.71) | MAPTKCNH2ALDH1A1 | |
| SCHEMBL3149580 | 0.82 | NR1D1 (0.47) | MAPTKCNH2CRHBPCRHR2AR | |
| SCHEMBL13262081 | 0.82 | HDAC1 (0.51) | HDAC3HDAC1HDAC2HDAC6NCOR2 | |
| SCHEMBL14776737 | 0.81 | CRHBP (0.57) | MAPTKCNH2CRHBPCRHR2AR | |
| SCHEMBL15759216 | 0.80 | HDAC1 (0.50) | HDAC3HDAC1HDAC2HDAC6NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001096-A | 4-amino-N-alkyl benzylamine preparation methood | SHENYANG RES INST CHEMICAL IND | 2015-10-28 | — | — | CN | disclosed |