Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482536 | 0.88 | ALDH1A1 (0.57) | ALDH1A1TDP1GAAHSD17B10TPMT | |
| SCHEMBL10978020 | 0.85 | HPGD (0.49) | ALDH1A1HSD17B10TPMTMAPTHPGD | |
| SCHEMBL483090 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TDP1GAAHSD17B10TPMT | |
| SCHEMBL1530412 | 0.77 | MAPT (0.37) | ALDH1A1TDP1GAAHSD17B10TNFRSF1A | |
| SCHEMBL1530410 | 0.77 | MAPT (0.37) | ALDH1A1TDP1GAAHSD17B10TNFRSF1A | |
| SCHEMBL1627319 | 0.73 | CA2 (0.43) | ALDH1A1TDP1HSD17B10MAPTERBB2 | |
| SCHEMBL295404 | 0.73 | ALDH1A1 (0.72) | ALDH1A1TDP1GAATNFRSF1AMAPT | |
| SCHEMBL18950804 | 0.73 | ALDH1A1 (0.45) | ALDH1A1TDP1GAA | |
| SCHEMBL1530698 | 0.71 | HSD17B10 (0.47) | ALDH1A1TDP1HSD17B10TPMTTNFRSF1A | |
| SCHEMBL5090250 | 0.71 | CA2 (0.55) | ALDH1A1TDP1GAAHSD17B10TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102448920-B | Antiviral compounds and uses thereof | ABBVIE (US) | 2016-04-06 | — | — | CN | disclosed |