Benzene

Benzene

SCHEMBL28042387

OB(OCl)c1ccccc1.c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 4/20 0.50
ENPP2 Q13822 4/20 0.50
ORAI1 Q96D31 3/20 0.50
ORAI2 Q96SN7 3/20 0.50
ORAI3 Q9BRQ5 3/20 0.50
PCSK9 Q8NBP7 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
CA1 P00915 5/20 0.38
CA2 P00918 4/20 0.38
MGLL Q99685 2/20 0.38
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
TRPM2 O94759 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL244920 1.00 TRPV6 (0.50) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL29658033 0.81 MGLL (0.62) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL2436493 0.81 MGLL (0.47) TRPV6ENPP2ORAI1ORAI2ORAI3
Trifluoromethylbenzene SCHEMBL28023606 0.80 TRPV6 (0.51) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL1848691 0.78 TRPV6 (0.63) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL20595738 0.77 CA1 (0.61) ENPP2CA7CA14CA1CA2
SCHEMBL28718291 0.76 TRPV6 (0.52) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL263598 0.76 TRPV6 (0.52) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL2316506 0.75 ORAI1 (0.54) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL28029418 0.75 CYP19A1 (0.34) MEN1ALDH1A1CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061306-A Boscalid preparation method LU YUEXIA 2015-11-18 CN claimed
CN-105061306-A Boscalid preparation method LU YUEXIA 2015-11-18 CN disclosed