Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066349 | 0.78 | LMNA (0.35) | CYP19A1LMNAMAPTALDH1A1CYP2D6 | |
| SCHEMBL16825623 | 0.76 | CYP1A2 (0.33) | CYP19A1LMNAMAPTALDH1A1CYP2D6 | |
| SCHEMBL1485477 | 0.76 | USP2 (0.34) | CYP19A1LMNAMAPTALDH1A1CYP2D6 | |
| Benzene SCHEMBL28042387 | 0.75 | TRPV6 (0.50) | ALDH1A1CYP1A2CYP3A4MEN1TSHR | |
| SCHEMBL244920 | 0.75 | TRPV6 (0.50) | ALDH1A1CYP1A2CYP3A4MEN1TSHR | |
| SCHEMBL8515494 | 0.74 | NAPRT (0.38) | CYP19A1LMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL28097813 | 0.73 | CYP1A2 (0.32) | LMNAMAPTCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL2316506 | 0.71 | ORAI1 (0.54) | — | |
| SCHEMBL2320469 | 0.71 | CA2 (0.54) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28687643 | 0.71 | NAPRT (0.37) | CYP19A1LMNAALDH1A1CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105163738-A | MK2 inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-16 | — | — | CN | disclosed |
| CN-105121418-A | Benzothiazol- 6 -yl acetic acid derivatives and their use for treating an hiv infection | GILEAD SCIENCES INC | 2015-12-02 | — | — | CN | disclosed |
| CN-102119158-B | Nitrogen-containing heterocyclic compound and organic electronic device using same | LG CHEM, LTD. (KR) | 2015-09-09 | — | — | CN | disclosed |