Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042191 | 0.83 | MAPT (0.46) | PLAUMAPTL3MBTL1SRD5A2KMT2A | |
| SCHEMBL1555065 | 0.81 | KMT2A (0.54) | PLAUMAPTL3MBTL1SRD5A2KMT2A | |
| SCHEMBL7928075 | 0.80 | KMT2A (0.53) | PLAUMAPTL3MBTL1SRD5A2KMT2A | |
| SCHEMBL11289129 | 0.79 | MAPT (0.54) | PLAUMAPTL3MBTL1SRD5A2KMT2A | |
| SCHEMBL165944 | 0.77 | CTBP2 (0.57) | MAPTL3MBTL1SRD5A2KMT2ARAB9A | |
| SCHEMBL30486043 | 0.77 | MAPT (0.51) | PLAUMAPTL3MBTL1SRD5A2KMT2A | |
| Methyl Alcohol SCHEMBL11602292 | 0.75 | MAPT (0.68) | PLAUMAPTL3MBTL1SRD5A2KMT2A | |
| SCHEMBL7199268 | 0.75 | MAPT (0.67) | PLAUMAPTL3MBTL1SRD5A2KMT2A | |
| SCHEMBL24800 | 0.75 | MAPT (0.73) | PLAUMAPTL3MBTL1SRD5A2KMT2A | |
| SCHEMBL6390145 | 0.74 | ALDH1A1 (0.56) | MAPTL3MBTL1SRD5A2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017254-A | 4-(4-((9H-purine-6-base)sulphur)phenyl)thiazolyl-2-amine derivative and preparation method and application thereof | UNIV SICHUAN | 2015-11-04 | — | — | CN | disclosed |