Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165944 | 0.85 | CTBP2 (0.57) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL160620 | 0.82 | NPC1 (0.68) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL7929656 | 0.81 | RAB9A (0.54) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL6546374 | 0.81 | GAA (0.51) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL6283593 | 0.81 | HCAR2 (0.47) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28042412 | 0.80 | PLAU (0.46) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28042191 | 0.80 | MAPT (0.46) | KMT2AMEN1RAB9ANPC1MAPT | |
| Methyl Alcohol SCHEMBL11602292 | 0.79 | MAPT (0.68) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL7541652 | 0.79 | RAB9A (0.52) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL7199268 | 0.79 | MAPT (0.67) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097158-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |