Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140677 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27916623 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27986862 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16003853 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27985361 | 0.79 | LTA4H (0.54) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7236001 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28814662 | 0.75 | LTA4H (0.44) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27916466 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27898682 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27898751 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LTA4HMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017254-A | 4-(4-((9H-purine-6-base)sulphur)phenyl)thiazolyl-2-amine derivative and preparation method and application thereof | UNIV SICHUAN | 2015-11-04 | — | — | CN | disclosed |