Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 3/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 10/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824358 | 0.85 | RNASEH1 (0.56) | NR1H2NR1H3KLKB1NPC1POLB | |
| SCHEMBL3104472 | 0.84 | SMN1; SMN2 (0.53) | NR1H2NR1H3KLKB1NPC1POLB | |
| SCHEMBL23337248 | 0.84 | HCAR2 (0.47) | KLKB1RIPK1 | |
| SCHEMBL19224520 | 0.83 | NR1H2 (0.56) | NR1H2NR1H3ALPLKLKB1NPC1 | |
| SCHEMBL24167145 | 0.80 | NR1H2 (0.53) | NR1H2NR1H3ALPLKLKB1NPC1 | |
| SCHEMBL23085471 | 0.80 | NR1H2 (0.53) | NR1H2NR1H3ALPLKLKB1NPC1 | |
| SCHEMBL30848602 | 0.79 | NR1H2 (0.51) | NR1H2NR1H3ALPLKLKB1NPC1 | |
| SCHEMBL553327 | 0.79 | TSHR (0.50) | NR1H2NR1H3KLKB1NPC1POLB | |
| SCHEMBL25586405 | 0.77 | KLKB1 (0.55) | NR1H2NR1H3KLKB1RIPK1HDAC6 | |
| SCHEMBL23081481 | 0.73 | RIPK1 (0.53) | NR1H2KLKB1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103073513-B | 1-replaces the chloro-2H-1 of-5-, 2,3-triazole-4-carboxylic acid derivative and preparation method thereof | ABA CHEMICALS CORPORATION (CN) | 2015-12-02 | — | — | CN | disclosed |