Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043071 | 0.90 | ABL1 (0.52) | GALR2MAPTKDM4EHSD17B10MCHR1 | |
| SCHEMBL28824391 | 0.84 | LMNA (0.46) | GALR2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL21434101 | 0.81 | KMT2A (0.61) | GALR2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL16014446 | 0.79 | GALR2 (0.46) | GALR2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL21434184 | 0.79 | GALR2 (0.53) | GALR2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL21434158 | 0.78 | TP53 (0.48) | GALR2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL3997867 | 0.77 | L3MBTL1 (0.50) | GALR2KDM4EMCHR1KMT2ACHRNA7 | |
| SCHEMBL28185039 | 0.77 | MAPT (0.48) | GALR2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL4358367 | 0.76 | KDM4E (0.50) | GALR2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL4358482 | 0.76 | ABL1 (0.58) | GALR2MAPTTP53KDM4EMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |