SCHEMBL28042952

SCHEMBL28042952

O=CC=CCc1ccccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.47
KMT2A Q03164 2/20 0.44
FOLH1 Q04609 1/20 0.39
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CYP2A6 P11509 1/20 0.38
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
ALOX5 P09917 1/20 0.36
MAPK1 P28482 1/20 0.36
PTGER1 P34995 2/20 0.36
PTGER4 P35408 2/20 0.36
PTGER3 P43115 2/20 0.36
PTGER2 P43116 2/20 0.36
HTR7 P34969 1/20 0.36
CYP11B1 P15538 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5889006 0.81 DPP4 (0.47) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL6206041 0.80 DPP4 (0.54) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL25795187 0.80 DPP4 (0.46) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL28593243 0.79 DPP4 (0.52) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL1515728 0.77 DPP4 (0.50) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL28348557 0.77 DPP4 (0.55) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL170431 0.77 DPP4 (0.55) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL8717020 0.77 DPP4 (0.50) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL10949035 0.76 KMT2A (0.51) DPP4KMT2AFOLH1PDCD1CD274
SCHEMBL10599731 0.76 PTGER4 (0.50) DPP4KMT2APDCD1CD274CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105152896-A Method for preparing 1, 4-diphenyl-2-benzophenone UNIV ZHEJIANG TECHNOLOGY 2015-12-16 CN claimed
CN-105152896-A Method for preparing 1, 4-diphenyl-2-benzophenone UNIV ZHEJIANG TECHNOLOGY 2015-12-16 CN disclosed