Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593243 | 0.98 | DPP4 (0.52) | DPP4KMT2AFOLH1PDCD1CD274 | |
| SCHEMBL1515728 | 0.96 | DPP4 (0.50) | DPP4KMT2AFOLH1PDCD1CD274 | |
| Carbamic Acid SCHEMBL27885337 | 0.91 | KMT2A (0.51) | DPP4KMT2AFOLH1PDCD1CD274 | |
| SCHEMBL30423174 | 0.88 | PTGER1 (0.42) | DPP4KMT2AFOLH1HTR7PTGER1 | |
| SCHEMBL1515759 | 0.87 | PTGER4 (0.57) | DPP4KMT2AFOLH1PDCD1CD274 | |
| SCHEMBL1515790 | 0.84 | FFAR1 (0.42) | DPP4KMT2AFOLH1SLC6A2SLC6A4 | |
| SCHEMBL28106097 | 0.84 | FOLH1 (0.42) | DPP4KMT2AFOLH1PDCD1CD274 | |
| SCHEMBL3905295 | 0.84 | PTGS2 (0.43) | DPP4KMT2ASLC6A4SLC6A3HTR7 | |
| SCHEMBL1497100 | 0.84 | CYP2C19 (0.48) | DPP4KMT2ASLC6A4SLC6A3HTR7 | |
| SCHEMBL2827860 | 0.83 | GABRA1 (0.50) | DPP4KMT2AFOLH1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104194613-A | Recoatable UV-curing colored one-step-coating aluminum powder paint and preparation method thereof | HIPRO POLYMER MATERIALS JIANGSU CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-103420916-A | Rapid preparation method for 1,2,3,4,5-tetra-substituted imidazole compound | UNIV LIAOCHENG | 2013-12-04 | — | — | CN | claimed |
| CN-103172583-A | Parecoxib preparation method | SHENZHEN JIFU PHARMACEUTICAL CO LTD | 2013-06-26 | — | — | CN | claimed |
| CN-102850848-A | UV gravure RFID printing ink and preparation method thereof | HANGHUA INK CHEMICAL CO LTD | 2013-01-02 | — | — | CN | claimed |
| CN-102329277-A | Method for preparing Parecoxib | HAINAN XIADI PHARMACEUTICAL CO LTD | 2012-01-25 | — | — | CN | claimed |
| US-20210186969-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-06-24 | — | — | US | disclosed |
| US-10980805-B2 | Aza-pyridone compounds and uses thereof | Janssen Biopharma, Inc. (US) | 2021-04-20 | — | — | US | disclosed |
| EP-3778603-A1 | 7,8-DIHYDRO-3H-PYRAZINO[1,2-B]PYRIDAZINE-3,5(6H)-DIONE COMPOUNDS AND USES THEREOF | Janssen BioPharma, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3030566-B1 | 7,8-DIHYDRO-3H-PYRAZINO[1,2-B]PYRIDAZINE-3,5(6H)-DIONE COMPOUNDS AND USES THEREOF | JANSSEN BIOPHARMA INC (US) | 2020-07-08 | — | — | EP | disclosed |
| US-10702523-B2 | AZA-pyridone compounds and uses thereof | Janssen Biopharma, Inc. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20200030328-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2020-01-30 | — | — | US | disclosed |
| US-20190314373-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | ALIOS BIOPHARMA, INC. (US) | 2019-10-17 | — | — | US | disclosed |
| WO-2004050631-A1 | SUBSTITUTED DIHYDROPHENANTHRIDINESUL FONAMIDES | WYETH (US) | 2004-06-17 | — | — | WO | disclosed |
| CN-1347406-A | Carbamic acid derivs. and their use as metabotropic glutamate receptor ligands | HOFFMANN LA ROCHE (CH) | 2002-05-01 | — | — | CN | disclosed |
| JP-2001233818-A | METHOD FOR PRODUCING BIPHENYLYLACETIC ACID | NIPPON STEEL CHEM CO LTD | 2001-08-28 | — | — | JP | disclosed |
| US-5523495-A | REACTING KETONE OR ALDEHYDE WITH A DIHALOPROPENE IN PRESENCE OF ZINC POWDER, WATER AND ACID YIELDS A HALOALLYLCARBINOL WHICH CAN BE DEHALOGENATED WITH A BASE, NONEXPLOSIVE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0404077-B1 | Process for producing propargylcarbinol compounds | SUMITOMO CHEMICAL CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5258529-A | Dehydrohalogenation of corresponding alkene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0404077-A1 | Process for producing propargylcarbinol compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-12-27 | — | — | EP | disclosed |
| US-4376769-A | Substituted imidazo thiazoles thiazines, thiazepines and thiazocines | SCHERING CORPORATION (US) | 1983-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030328-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | PNPO, ITPA, PDXK | DPP4 129/4885KMT2A 1791/4885FOLH1 4709/4885 |
| US-10980805-B2 | Aza-pyridone compounds and uses thereof | PNPO, ITPA, PDXK | DPP4 129/4885KMT2A 1791/4885FOLH1 4709/4885 |
| US-20190314373-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | PNPO, ITPA, PDXK | DPP4 129/4885KMT2A 1791/4885FOLH1 4709/4885 |
| US-20210186969-A1 | AZA-PYRIDONE COMPOUNDS AND USES THEREOF | PNPO, ITPA, PDXK | DPP4 129/4885KMT2A 1791/4885FOLH1 4709/4885 |
| US-10702523-B2 | AZA-pyridone compounds and uses thereof | PNPO, ITPA, PDXK | DPP4 129/4885KMT2A 1791/4885FOLH1 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.