Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719081 | 0.83 | MAPT (0.56) | APPALDH1A1CYP3A4CYP2D6ALOX15 | |
| Iodide SCHEMBL8929776 | 0.81 | MAPT (0.54) | APPALDH1A1CYP3A4CYP2D6ALOX15 | |
| Hydrochloric Acid SCHEMBL9634629 | 0.81 | MAPT (0.54) | APPALDH1A1CYP3A4CYP2D6ALOX15 | |
| SCHEMBL2118962 | 0.79 | KAT8 (0.59) | MMP13APPMMP2MMP9MMP8 | |
| SCHEMBL1228438 | 0.79 | KAT8 (0.59) | MMP13APPMMP2MMP9MMP8 | |
| SCHEMBL7896212 | 0.76 | MAPT (0.47) | MMP13APPMMP2MMP9MMP8 | |
| Pyrene SCHEMBL28845423 | 0.75 | MAPT (0.49) | APPALDH1A1CYP3A4CYP2D6ALOX15 | |
| 2-Mercaptobenzothiazole SCHEMBL28269969 | 0.73 | MMP13 (0.66) | MMP13APPMMP2MMP9MMP8 | |
| Nitrobenzene SCHEMBL28543842 | 0.72 | ALDH1A1 (0.89) | ALDH1A1CYP2C19MEN1KMT2AMAPK1 | |
| Nitrobenzene SCHEMBL27522452 | 0.72 | ALDH1A1 (0.89) | ALDH1A1CYP2C19MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237494-A | Alkali compound containing benzo thiazole ring salicylaldehyde Schiff and preparation method thereof | SHANGRAO NORMAL UNIVERSITY | 2016-01-13 | — | — | CN | disclosed |