Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043042 | 0.75 | CA2 (0.45) | CA2CA12CA1CA9CA4 | |
| SCHEMBL5199952 | 0.71 | CA2 (0.34) | CA2CA12CA1CA9CA4 | |
| SCHEMBL6671590 | 0.70 | CA1 (0.44) | CA2CA12CA1CA9CA4 | |
| SCHEMBL3807203 | 0.69 | CA2 (0.41) | CA2CA12CA1CA9CA4 | |
| SCHEMBL3805419 | 0.69 | CA2 (0.50) | CA2CA12CA1CA9CA4 | |
| SCHEMBL28043026 | 0.68 | CA1 (0.41) | CA2CA12CA1CA9CA4 | |
| SCHEMBL4574416 | 0.67 | CA2 (0.34) | CA2CA12CA1CA9CA4 | |
| SCHEMBL6290698 | 0.67 | PDIA6 (0.40) | CA2CA12CA1CA9CA4 | |
| SCHEMBL28043283 | 0.67 | — | — | |
| SCHEMBL27993136 | 0.66 | PSIP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102197023-B | Compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-12-16 | — | — | CN | disclosed |