Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | BCHE | P06276 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762378 | 0.74 | MAPT (0.44) | MAOBAKT1MAPTBCHERAB9A | |
| SCHEMBL6270921 | 0.73 | MAPT (0.46) | MAOBMAPTBCHERAB9ANPC1 | |
| SCHEMBL29945646 | 0.73 | MAPT (0.46) | MAOBMAPTBCHERAB9ANPC1 | |
| SCHEMBL6534548 | 0.73 | MAPT (0.43) | MAOBAKT1MAPTBCHERAB9A | |
| SCHEMBL28010219 | 0.72 | RECQL (0.43) | MAOBMAPTBCHERAB9ANPC1 | |
| SCHEMBL30385151 | 0.72 | RECQL (0.43) | MAOBMAPTBCHERAB9ANPC1 | |
| SCHEMBL1576393 | 0.70 | BCHE (0.41) | MAPTBCHERAB9ANPC1KMT2A | |
| SCHEMBL27929731 | 0.69 | MAPT (0.38) | MAOBAKT1MAPTBCHERAB9A | |
| SCHEMBL1576591 | 0.67 | TUBB4A (0.39) | MAOBAKT1MAPTBCHERAB9A | |
| SCHEMBL29047175 | 0.65 | L3MBTL1 (0.35) | MAPTRAB9ANPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153090-A | 4'-bromo-7-isoamylene oxo-2,3-flavanone and preparation method as well as application in preparing antidepressant drugs | UNIV ZHEJIANG OCEAN | 2015-12-16 | — | — | CN | claimed |
| CN-105153090-A | 4'-bromo-7-isoamylene oxo-2,3-flavanone and preparation method as well as application in preparing antidepressant drugs | UNIV ZHEJIANG OCEAN | 2015-12-16 | — | — | CN | disclosed |