Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15937905 | 0.83 | ERN1 (0.54) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL31341046 | 0.81 | EGFR (0.48) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL13343663 | 0.81 | EGFR (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL3564032 | 0.81 | EGFR (0.41) | EGFRTDP1NPC1RAB9A | |
| SCHEMBL5840781 | 0.78 | ADRB2 (0.60) | KDM4EEGFRADRB2L3MBTL1GAA | |
| SCHEMBL28794966 | 0.78 | EGFR (0.44) | KDM4EEGFRADRB2L3MBTL1GAA | |
| SCHEMBL28598178 | 0.76 | PTGER1 (0.62) | KDM4EEGFRL3MBTL1GAATDP1 | |
| SCHEMBL5490744 | 0.76 | TRIM24 (0.52) | DRD1KDM4EAXLMEN1KMT2A | |
| SCHEMBL5988943 | 0.76 | KDM4E (0.47) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29888111 | 0.75 | ALDH1A1 (0.51) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051048-A | 1-hydroxy-benzoxaboroles as antiparasitic agents | LILLY CO ELI | 2015-11-11 | — | — | CN | disclosed |