Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257743 | 0.80 | KDM4E (0.68) | KDM4EMEN1KMT2AS1PR5 | |
| SCHEMBL22863936 | 0.77 | S1PR5 (0.70) | KDM4ESLC18A3SIGMAR1MEN1KMT2A | |
| SCHEMBL28046102 | 0.76 | KDM4E (0.47) | KDM4ESLC18A3SIGMAR1 | |
| SCHEMBL22468572 | 0.75 | KDM4E (0.53) | KDM4ESLC18A3SIGMAR1MEN1KMT2A | |
| SCHEMBL13285816 | 0.75 | KDM4E (0.72) | KDM4EMEN1KMT2AS1PR5 | |
| SCHEMBL22488324 | 0.75 | KDM4E (0.53) | KDM4ESLC18A3SIGMAR1MEN1KMT2A | |
| SCHEMBL22864003 | 0.74 | KDM4E (0.52) | KDM4ESLC18A3SIGMAR1DRD2S1PR5 | |
| SCHEMBL22488321 | 0.74 | ALDH1A1 (0.57) | KDM4ESLC18A3SIGMAR1MEN1KMT2A | |
| SCHEMBL22488317 | 0.74 | ALDH1A1 (0.57) | KDM4ESLC18A3SIGMAR1MEN1KMT2A | |
| SCHEMBL13650590 | 0.74 | ALDH1A1 (0.57) | KDM4ESLC18A3SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164127-A | Bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |