Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864002 | 0.86 | KDM4E (0.46) | KDM4ESIGMAR1SLC18A3DRD2 | |
| SCHEMBL22863936 | 0.84 | S1PR5 (0.70) | KDM4ES1PR5SIGMAR1SLC18A3 | |
| SCHEMBL6990156 | 0.77 | S1PR5 (0.67) | KDM4ES1PR5SIGMAR1SLC18A3 | |
| Trifluoroacetic Acid SCHEMBL1921476 | 0.76 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL501146 | 0.75 | S1PR5 (0.54) | S1PR5 | |
| SCHEMBL501147 | 0.75 | S1PR5 (0.54) | S1PR5 | |
| SCHEMBL4264860 | 0.75 | S1PR5 (0.54) | S1PR5 | |
| SCHEMBL27549340 | 0.75 | KDM4E (0.76) | KDM4ES1PR5 | |
| SCHEMBL28043174 | 0.74 | KDM4E (0.49) | KDM4ES1PR5SIGMAR1SLC18A3DRD2 | |
| SCHEMBL22488317 | 0.74 | ALDH1A1 (0.57) | KDM4ESIGMAR1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003398-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-01-07 | — | — | WO | disclosed |