Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023906 | 0.88 | MMP1 (0.46) | KDM4ESIGMAR1MMP1MMP13POLB | |
| SCHEMBL28036651 | 0.84 | SIGMAR1 (0.46) | KDM4ESIGMAR1PKM | |
| SCHEMBL5191850 | 0.79 | LTA4H (0.49) | KDM4ESIGMAR1POLBPKMSLC18A3 | |
| SCHEMBL27465272 | 0.79 | SIGMAR1 (0.45) | KDM4ESIGMAR1 | |
| SCHEMBL28257743 | 0.77 | KDM4E (0.68) | KDM4E | |
| SCHEMBL28043174 | 0.76 | KDM4E (0.49) | KDM4ESIGMAR1SLC18A3 | |
| SCHEMBL27511718 | 0.76 | SIGMAR1 (0.47) | SIGMAR1SMN1; SMN2 | |
| SCHEMBL27486296 | 0.76 | SIGMAR1 (0.47) | SIGMAR1SMN1; SMN2 | |
| SCHEMBL21262108 | 0.74 | SIGMAR1 (0.49) | SIGMAR1POLBPKMSMN1; SMN2 | |
| SCHEMBL27739345 | 0.73 | MAPT (0.43) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105229013-A | Epidithio-dioxypiperazine piperazine compound or its derivative, and uses thereof | EWHA IND COLLABORATION | 2016-01-06 | — | — | CN | disclosed |