Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366125 | 0.81 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL27815518 | 0.81 | ALDH1A1 (0.39) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL27810288 | 0.81 | PTPRB (0.36) | ALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL27924510 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL28043189 | 0.80 | KCNH2 (0.35) | ALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL27760330 | 0.79 | PTPRB (0.39) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL27812400 | 0.79 | GAA (0.33) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16123392 | 0.75 | SIRT1 (0.45) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL21747566 | 0.74 | GRM5 (0.33) | ALDH1A1GAA | |
| SCHEMBL27703575 | 0.72 | KDM1A (0.38) | ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105163738-A | MK2 inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-16 | — | — | CN | disclosed |