Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043182 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL28366435 | 0.77 | GABRA5 (0.36) | KDM4EALDH1A1GABRA5GABRB2HSD17B10 | |
| SCHEMBL28361587 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL16386285 | 0.72 | CYP2D6 (0.44) | — | |
| SCHEMBL27612020 | 0.72 | GABRA5 (0.44) | KDM4EALDH1A1GABRA5GABRB2HSD17B10 | |
| SCHEMBL28803151 | 0.71 | AOC3 (0.33) | GABRA5GABRB2HSD17B10 | |
| SCHEMBL28316724 | 0.71 | GABRA5 (0.32) | ALDH1A1GABRA5GABRB2HSD17B10 | |
| SCHEMBL16095853 | 0.70 | SMN1; SMN2 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL20751484 | 0.69 | HDAC6 (0.39) | GABRA5GABRB2HSD17B10 | |
| SCHEMBL27969194 | 0.69 | SLC6A3 (0.32) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746424-A | MK2 inhibitors and uses thereof | 西建卡尔有限责任公司 | 2020-02-04 | — | — | CN | disclosed |