SCHEMBL28043240

SCHEMBL28043240

CCCC(CCC)COC(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
CA2 P00918 3/20 0.47
CA1 P00915 2/20 0.47
CA12 O43570 1/20 0.47
CA7 P43166 1/20 0.47
CA14 Q9ULX7 1/20 0.47
LMNA P02545 4/20 0.41
HSD17B10 Q99714 1/20 0.41
TSHR P16473 7/20 0.40
CYP3A4 P08684 5/20 0.40
TDP1 Q9NUW8 3/20 0.40
ATM Q13315 1/20 0.40
CHRNB2 P17787 2/20 0.39
CHRNA4 P43681 2/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
NPSR1 Q6W5P4 3/20 0.38
CYP1A2 P05177 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24733682 0.91 CYP3A4 (0.50) ALOX15CA2CA1CA12CA7
SCHEMBL836498 0.90 CA2 (0.40) ALOX15CA2CA1CA12CA7
Iodide SCHEMBL872505 0.90 CYP3A4 (0.49) ALOX15CA2CA1CA12CA7
SCHEMBL8942996 0.84 PRSS1 (0.50) ALOX15CA2LMNATSHRCYP3A4
SCHEMBL224633 0.81 ALOX15 (0.52) ALOX15CA2LMNAHSD17B10TSHR
SCHEMBL10581132 0.81 CYP3A4 (0.49) ALOX15CA2CA1LMNAHSD17B10
SCHEMBL224692 0.80 ALOX15 (0.46) ALOX15CA2CA1LMNAHSD17B10
SCHEMBL6671734 0.80 ALOX15 (0.46) ALOX15CA2CA1LMNAHSD17B10
SCHEMBL467542 0.79 CYP3A4 (0.66) CA2CA1LMNAHSD17B10TSHR
SCHEMBL10262639 0.79 ALDH1A1 (0.46) CA2CA1CA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113840591-A Oil-in-water macroemulsion 西姆莱斯股份公司 2021-12-24 CN disclosed
CN-102197023-B Compounds for the treatment of ophthalmic diseases and disorders ACUCELA INC. (US) 2015-12-16 CN disclosed