Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | CES1 | P23141 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043143 | 0.92 | HDAC3 (0.63) | MEN1KMT2ACYP3A4HPGDMAPK1 | |
| SCHEMBL28054494 | 0.86 | HDAC3 (0.57) | MEN1KMT2ACYP3A4HPGDMAPK1 | |
| SCHEMBL2005451 | 0.85 | MEN1 (0.94) | MEN1KMT2ACYP3A4HPGDMAPK1 | |
| SCHEMBL27646618 | 0.84 | PLAU (0.60) | MEN1KMT2ACYP3A4HPGDMAPK1 | |
| SCHEMBL203283 | 0.83 | ALDH1A1 (0.61) | MEN1KMT2AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL13885490 | 0.83 | CES2 (0.65) | CES1KDM4ERAB9ACYP1A2CYP2D6 | |
| Dibenzoylmethane SCHEMBL39582 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP3A4HPGDMAPK1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP3A4HPGDMAPK1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP3A4HPGDMAPK1 | |
| SCHEMBL14230630 | 0.82 | MEN1 (0.71) | MEN1KMT2ACYP3A4HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105523874-A | Preparation method of 2,2-dihalo-1,3-dicarbonyl derivatives | ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV | 2016-04-27 | — | — | CN | claimed |
| CN-105503635-A | Preparation method for 2-amidoformyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-04-20 | — | — | CN | claimed |
| CN-105503945-A | Method for preparing 2-phosphonic acid ester base-1, 3-dicarbonyl derivative | UNIV SOOCHOW | 2016-04-20 | — | — | CN | claimed |
| CN-105461496-A | Preparation method for 2-halogenated-1,3-dicarbonyl derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-105348060-A | Preparation method of 1,2-diketone derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-02-24 | — | — | CN | claimed |
| CN-105254483-A | Method for preparing 2-methyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-01-20 | — | — | CN | claimed |
| CN-105348060-B | A kind of preparation method of 1,2 derovatives | 江苏强盛功能化学股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-105461496-B | A kind of preparation method of the Dicarbonyl derivatives of 2 halo 1,3 | 江苏强盛功能化学股份有限公司 | 2018-01-30 | — | — | CN | disclosed |
| CN-105254483-B | A kind of method for preparing the Dicarbonyl derivatives of 2 methyl 1,3 | 苏州大学 | 2017-11-03 | — | — | CN | disclosed |
| CN-105503635-B | A kind of preparation method of the Dicarbonyl derivatives of 2 amido formacyl 1,3 | 苏州大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-105503945-B | A kind of method for preparing the Dicarbonyl derivatives of 2 phosphonate group 1,3 | 苏州大学 | 2017-09-05 | — | — | CN | disclosed |
| CN-105523874-A | Preparation method of 2,2-dihalo-1,3-dicarbonyl derivatives | ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV | 2016-04-27 | — | — | CN | disclosed |
| CN-105503635-A | Preparation method for 2-amidoformyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-04-20 | — | — | CN | disclosed |
| CN-105503945-A | Method for preparing 2-phosphonic acid ester base-1, 3-dicarbonyl derivative | UNIV SOOCHOW | 2016-04-20 | — | — | CN | disclosed |
| CN-105461496-A | Preparation method for 2-halogenated-1,3-dicarbonyl derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-105348060-A | Preparation method of 1,2-diketone derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-02-24 | — | — | CN | disclosed |
| CN-105254483-A | Method for preparing 2-methyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-01-20 | — | — | CN | disclosed |