Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058837 | 0.83 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2HTTHPGDALDH1A1 | |
| SCHEMBL1397470 | 0.78 | KMT2A (0.58) | KMT2APGRADRA2AADRA2BHTR2A | |
| SCHEMBL28043314 | 0.78 | KMT2A (0.53) | KMT2APGRADRA2AADRA2BHTR2A | |
| SCHEMBL29588714 | 0.76 | KMT2A (0.46) | KMT2APGRADRA2AADRA2BHTR2A | |
| SCHEMBL13871510 | 0.76 | KMT2A (0.46) | KMT2APGRADRA2AADRA2BHTR2A | |
| SCHEMBL1851110 | 0.75 | MAPT (0.57) | KMT2ALMNAMAPTATMTDP1 | |
| Lactic Acid SCHEMBL28343599 | 0.73 | FOLH1 (0.47) | KMT2ALMNAMAPTHTTALDH1A1 | |
| SCHEMBL1395206 | 0.73 | LMNA (0.52) | HTR2ALMNASMN1; SMN2MAPK1CES2 | |
| SCHEMBL30395952 | 0.73 | DPP8 (0.46) | KMT2APGRADRA2AADRA2BHTR2A | |
| SCHEMBL136079 | 0.73 | FOLH1 (0.59) | MAPTSMN1; SMN2HTTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254483-A | Method for preparing 2-methyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-01-20 | — | — | CN | disclosed |