SCHEMBL1397470

SCHEMBL1397470

CC(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
LMNA P02545 4/20 0.56
MAPT P10636 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
ATM Q13315 2/20 0.56
XBP1 P17861 1/20 0.56
PGR P06401 1/20 0.55
ADRA2A P08913 1/20 0.55
ADRA2B P18089 1/20 0.55
HTR2A P28223 1/20 0.55
HRH1 P35367 1/20 0.55
KCNH2 Q12809 1/20 0.55
CES2 O00748 4/20 0.54
CES1 P23141 4/20 0.54
ALDH1A1 P00352 3/20 0.50
TSHR P16473 3/20 0.50
DAO P14920 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20944778 0.90 KMT2A (0.55) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL649287 0.90 KMT2A (0.55) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL8823334 0.90 KMT2A (0.55) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL3274886 0.90 KMT2A (0.55) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL7867720 0.89 CES2 (0.59) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL744661 0.89 CES2 (0.63) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL28458281 0.88 KMT2A (0.53) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL27493547 0.87 CES2 (0.61) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL4971852 0.87 CYP2C9 (0.52) KMT2ATDP1L3MBTL1LMNAMAPT
SCHEMBL28043313 0.87 SMN1; SMN2 (0.53) KMT2ATDP1L3MBTL1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200361892-A1 POLYCYCLOCARBONATE COMPOUNDS AND POLYMERS FORMED THEREFROM SWIMC LLC (US) 2020-11-19 US claimed
US-10000461-B2 Polycyclocarbonate compounds and polymers formed therefrom SWIMC LLC (US) 2018-06-19 US claimed
US-20170096408-A1 POLYCYCLOCARBONATE COMPOUNDS AND POLYMERS FORMED THEREFROM VALSPAR SOURCING, INC. (US) 2017-04-06 US claimed
EP-3134484-A1 POLYCYCLOCARBONATE COMPOUNDS AND POLYMERS FORMED THEREFROM Valspar Sourcing, Inc. (US) 2017-03-01 EP claimed
WO-2015164692-A1 POLYCYCLOCARBONATE COMPOUNDS AND POLYMERS FORMED THEREFROM VALSPAR SOURCING, INC. (US) 2015-10-29 WO claimed
CN-102300549-B Water-in-oil-type emulsion sunscreen cosmetic SHISEIDO CO LTD 2014-08-20 CN claimed
CN-103705398-A Cosmetic emulsion with polyacrylate BEIERSDORF AG 2014-04-09 CN claimed
CN-102811703-A Sun protection compositions BAYER MATERIALSCIENCE AG 2012-12-05 CN claimed
CN-102791248-A Stabilization of cosmetic compositions BASF SE 2012-11-21 CN claimed
CN-101854904-B Stabilization of cosmetic compositions BASF SE 2012-08-15 CN claimed
WO-2000023044-A1 UV PROTECTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-04-27 WO claimed
CN-1235547-A Antiherpetic pharmaceutical compositions containing acyclovir for topical applicators RECORDATI CHEM PHARM (CH) 1999-11-17 CN claimed
CN-1222343-A Photoprotective compositions and cosmetic uses OREAL (FR) 1999-07-14 CN claimed
CN-1208342-A Stabilised sunscreen compositions OREAL (FR) 1999-02-17 CN claimed
CN-1116520-A Skin protecting composition containing acid hydrophilic agent for cosmetic use and application of same OREAL (FR) 1996-02-14 CN claimed
EP-0516743-B1 TRANSITION METAL CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC (US) 1994-09-14 EP claimed
EP-0516743-A1 TRANSITION METAL CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION. EXXON CHEMICAL PATENTS INC (US) 1992-12-09 EP claimed
US-5145662-A Ujv rad filters L'OREAL (FR) 1992-09-08 US claimed
WO-1991013074-A2 TRANSITION METAL CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1991-09-05 WO claimed
US-5021595-A Coordination catalysts based on a transition metal compound chelated with a ligand; durability; alpha-unsaturated hydrocarbons EXXON CHEMICAL PATENTS INC. (US) 1991-06-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170096408-A1 POLYCYCLOCARBONATE COMPOUNDS AND POLYMERS FORMED THEREFROM PICALM, PCLAF, PBRM1 KMT2A 2565/4885TDP1 3119/4885L3MBTL1 4199/4885
US-20200361892-A1 POLYCYCLOCARBONATE COMPOUNDS AND POLYMERS FORMED THEREFROM PICALM, PCLAF, PBRM1 KMT2A 2565/4885TDP1 3119/4885L3MBTL1 4199/4885
US-10000461-B2 Polycyclocarbonate compounds and polymers formed therefrom PICALM, PCLAF, PBRM1 KMT2A 2565/4885TDP1 3119/4885L3MBTL1 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.