Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178296 | 0.82 | CA2 (0.61) | ALDH1A1CYP3A4LMNAHTTGAA | |
| SCHEMBL92071 | 0.80 | ALDH1A1 (0.95) | ALDH1A1MEN1MAPTTHRBKMT2A | |
| SCHEMBL30966043 | 0.79 | CA1 (0.42) | ALDH1A1MEN1MAPTTHRBKMT2A | |
| SCHEMBL29186662 | 0.79 | TUBB1 (0.54) | ALDH1A1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL15938210 | 0.78 | ALDH1A1 (0.76) | ALDH1A1MEN1MAPTTHRBKMT2A | |
| Hydrochloric Acid SCHEMBL2585553 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MEN1MAPTTHRBKMT2A | |
| SCHEMBL28683526 | 0.78 | ALDH1A1 (0.91) | ALDH1A1MEN1MAPTTHRBKMT2A | |
| SCHEMBL31618409 | 0.78 | CA12 (0.41) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL22042263 | 0.78 | LMNA (0.47) | LMNAHTTCA1CA2TUBB1 | |
| SCHEMBL30504353 | 0.78 | LMNA (0.47) | LMNAHTTCA1CA2TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105163738-A | MK2 inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-16 | — | — | CN | disclosed |