Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997329 | 0.78 | BRD4 (0.38) | ALDH1A1MEN1NPC1MAPTHTT | |
| SCHEMBL5100729 | 0.77 | BACE1 (0.39) | BACE1ALDH1A1PTPN1MEN1APAF1 | |
| SCHEMBL27676264 | 0.75 | HPRT1 (0.39) | BACE1ALDH1A1PTPN1MEN1APAF1 | |
| SCHEMBL22689862 | 0.75 | CYP2A6 (0.41) | BACE1ALDH1A1PTPN1MEN1APAF1 | |
| SCHEMBL28767216 | 0.72 | PTPN1 (0.40) | ALDH1A1PTPN1MEN1KMT2AALOX5 | |
| SCHEMBL3843630 | 0.71 | BACE1 (0.34) | BACE1ALDH1A1PTPN1MEN1APAF1 | |
| SCHEMBL11233522 | 0.71 | PDE4B (0.40) | BACE1ALDH1A1METAP2MEN1NPC1 | |
| SCHEMBL22064850 | 0.70 | ALDH1A1 (0.47) | BACE1ALDH1A1PTPN1MEN1APAF1 | |
| SCHEMBL693994 | 0.70 | ALDH1A1 (0.39) | BACE1ALDH1A1METAP2MEN1NPC1 | |
| SCHEMBL454694 | 0.67 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037072-A | Synthetic method for 1,3,5-triarylbenzene compound | UNIV HUAQIAO | 2015-11-11 | — | — | CN | disclosed |