SCHEMBL11233522

SCHEMBL11233522

COc1[c]cc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.40
PDE4A P27815 2/20 0.40
PDE4C Q08493 2/20 0.40
PDE4D Q08499 2/20 0.40
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 1/20 0.39
ATM Q13315 1/20 0.39
SQOR Q9Y6N5 2/20 0.38
BACE1 P56817 2/20 0.38
IKBKB O14920 1/20 0.35
PIN1 Q13526 1/20 0.35
FYN P06241 1/20 0.35
ABL1 P00519 1/20 0.34
ABCB1 P08183 1/20 0.34
BCR P11274 1/20 0.34
ALDH1A1 P00352 2/20 0.34
CASP1 P29466 1/20 0.34
ACACA Q13085 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7459961 0.84 BACE1 (0.44) MAPTMEN1TSHRKMT2AATM
SCHEMBL21331773 0.76 BACE1 (0.42) PDE4BPDE4APDE4CPDE4DMAPT
SCHEMBL3535486 0.73 ALDH1A1 (0.39) PDE4BPDE4APDE4CPDE4DMAPT
SCHEMBL5100729 0.72 BACE1 (0.39) MAPTMEN1KMT2AATMBACE1
SCHEMBL28171307 0.72 BACE1 (0.47) MAPTKMT2ABACE1ABL1ABCB1
SCHEMBL22689862 0.71 CYP2A6 (0.41) MAPTMEN1KMT2AATMBACE1
SCHEMBL7823588 0.70 PDE4B (0.40) PDE4BPDE4APDE4CPDE4DMAPT
SCHEMBL2096573 0.70 PDE4B (0.55) PDE4BPDE4APDE4CPDE4DMAPT
SCHEMBL22026702 0.70 TRPA1 (0.53) MAPTABL1ABCB1BCRKDM4E
SCHEMBL6183394 0.69 PDE4B (0.46) PDE4BPDE4APDE4CPDE4DMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4334005-A Transition metal photoreduction systems and processes EASTMAN KODAK COMPANY (US) 1982-06-08 US disclosed
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US disclosed
US-4314019-A NONSILVER PHOTOGRAPHY; COBALT AMMINE COMPLEXES) QUINONE REDUCING AGENTS EASTMAN KODAK COMPANY (US) 1982-02-02 US disclosed
US-4284704-A Photographic elements with incorporated hydrogen source photoreductant and tetrazolium salt EASTMAN KODAK COMPANY (US) 1981-08-18 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed