SCHEMBL3843630

SCHEMBL3843630

C#Cc1[c]cc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.34
MAPT P10636 3/20 0.34
RAB9A P51151 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP2A6 P11509 1/20 0.33
PTPN1 P18031 1/20 0.33
SMARCA2 P51531 1/20 0.32
SMARCA4 P51532 1/20 0.32
PBRM1 Q86U86 1/20 0.32
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
XBP1 P17861 1/20 0.32
PTBP1 P26599 1/20 0.32
HTT P42858 1/20 0.32
GALK1 P51570 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843439 0.74 CYP2A6 (0.33) BACE1MAPTCYP2A6LMNAHTT
SCHEMBL2423292 0.73 CYP2A6 (0.40) BACE1ALDH1A1CYP2A6HPGD
SCHEMBL5100729 0.72 BACE1 (0.39) BACE1MAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL22689862 0.71 CYP2A6 (0.41) BACE1MAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL3849720 0.70 ALDH1A1 (0.34) MAPTRAB9AL3MBTL1ALDH1A1NPSR1
SCHEMBL4369816 0.70 PTPN1 (0.41) BACE1MAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL3850051 0.67 CYP2A6 (0.33) BACE1MAPTCYP2A6LMNAHTT
SCHEMBL11233522 0.67 PDE4B (0.40) BACE1MAPTRAB9AALDH1A1MEN1
Biphenyl SCHEMBL27831016 0.65 ALDH1A1 (0.60) BACE1MAPTALDH1A1CYP2A6ATM
SCHEMBL15901560 0.65 BACE1 (0.44) BACE1MAPTL3MBTL1ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed