Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071278 | 0.82 | HTT (0.33) | TSHRHCRTR1HCRTR2 | |
| SCHEMBL28940883 | 0.81 | GABRA5 (0.37) | GABRA5GABRB2GABRA1GABRA4HSD17B10 | |
| SCHEMBL27940385 | 0.78 | GABRA5 (0.38) | GABRA5GABRB2GABRA1GABRA4HSD17B10 | |
| SCHEMBL30260445 | 0.77 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL31292217 | 0.77 | KDM4E (0.38) | HSD17B10ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL27837903 | 0.77 | GABRA5 (0.37) | GABRA5GABRB2GABRA1GABRA4HSD17B10 | |
| SCHEMBL27940310 | 0.77 | AGBL2 (0.38) | GABRA5GABRB2GABRA1GABRA4HSD17B10 | |
| SCHEMBL1363917 | 0.75 | AGBL2 (0.41) | GABRA5GABRB2GABRA1GABRA4HSD17B10 | |
| SCHEMBL29593515 | 0.75 | AGBL2 (0.41) | GABRA5GABRB2GABRA1GABRA4HSD17B10 | |
| SCHEMBL2729582 | 0.75 | GABRA5 (0.53) | GABRA5GABRB2GABRA1GABRA4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732583-B | TRPV4 antagonist | GLAXOSMITHKLINE LLC (GB) | 2015-12-23 | — | — | CN | disclosed |