SCHEMBL30260445

SCHEMBL30260445

CNC(=O)Cc1cnc(Br)cn1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.33
HCRTR2 O43614 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31292217 0.79 KDM4E (0.38) HCRTR1HCRTR2
SCHEMBL30260433 0.79 SIRT6 (0.43)
SCHEMBL3662503 0.77 GLS (0.45)
SCHEMBL28043641 0.77 GABRA5 (0.36) HCRTR1HCRTR2
SCHEMBL4071278 0.76 HTT (0.33) HCRTR1HCRTR2
SCHEMBL16891679 0.73 HDAC3 (0.43)
SCHEMBL19781866 0.72 SMN1; SMN2 (0.45) HCRTR1HCRTR2
SCHEMBL30731116 0.69 KDM4E (0.43)
SCHEMBL23881399 0.68 CXCR2 (0.41)
SCHEMBL12424191 0.68 NPC1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115715287-A Substituted N- (methyl-d 3) pyridazine-3-carboxamide or N- (methyl-d 3) -nicotinamide compounds as IL-12, IL-23 and/or IFN alpha modulators 百时美施贵宝公司 2023-02-24 CN disclosed