Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 7/20 | 0.48 |
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | CA9 | Q16790 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616637 | 0.81 | CYP1A2 (0.56) | L3MBTL1MAPK1HTTLMNACYP1A2 | |
| SCHEMBL4616638 | 0.81 | CYP1A2 (0.56) | L3MBTL1MAPK1HTTLMNACYP1A2 | |
| SCHEMBL23728038 | 0.77 | CYP1A2 (0.51) | L3MBTL1MAPK1HTTLMNACYP1A2 | |
| SCHEMBL23728036 | 0.77 | CYP1A2 (0.51) | L3MBTL1MAPK1HTTLMNACYP1A2 | |
| SCHEMBL5280714 | 0.76 | CYP1A2 (0.50) | L3MBTL1MAPK1HTTLMNACYP1A2 | |
| SCHEMBL3969682 | 0.75 | MAPK1 (0.61) | L3MBTL1MAPK1HTTLMNACA12 | |
| SCHEMBL3969684 | 0.75 | MAPK1 (0.61) | L3MBTL1MAPK1HTTLMNACA12 | |
| SCHEMBL5708484 | 0.73 | LMNA (0.48) | L3MBTL1MAPK1HTTLMNACYP1A2 | |
| SCHEMBL23749759 | 0.72 | CYP1A2 (0.46) | L3MBTL1MAPK1HTTLMNACYP1A2 | |
| SCHEMBL5708470 | 0.72 | LMNA (0.47) | L3MBTL1HTTLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130923-A | Preparation method of polysubstituted 2-iminothiazole compound | UNIV ZHEJIANG TECHNOLOGY | 2015-12-09 | — | — | CN | disclosed |