Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805614 | 0.98 | PLA2G2A (0.41) | GAAHTTCNR2PLA2G2AKDM4E | |
| SCHEMBL2804614 | 0.82 | GAA (0.43) | GAAHTTKDM4EHSD17B10PTGER4 | |
| SCHEMBL2804380 | 0.73 | CNR2 (0.51) | GAACNR2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2808268 | 0.73 | PLA2G4A (0.45) | PLA2G2AALDH1A1TSHR | |
| SCHEMBL2809729 | 0.73 | PLA2G4A (0.50) | PLA2G2A | |
| SCHEMBL2805611 | 0.72 | CNR2 (0.50) | GAACNR2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2806883 | 0.72 | PLA2G2A (0.43) | GAAHTTPLA2G2AKDM4EHSD17B10 | |
| SCHEMBL2807309 | 0.72 | PLA2G2A (0.43) | GAAHTTPLA2G2AKDM4EHSD17B10 | |
| SCHEMBL2807126 | 0.71 | PLA2G4A (0.50) | PLA2G2A | |
| SCHEMBL2806144 | 0.70 | PLA2G4A (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240718-A1 | NOVEL HETEROARYL-SUBSTITUTED ACETONE DERIVATIVE, SUITABLE FOR INHIBITING PHOSPHOLIPASE A2 | WESTFALISCHE WILHELMS UNIVERSITÄT MÜNSTER (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240718-A1 | NOVEL HETEROARYL-SUBSTITUTED ACETONE DERIVATIVE, SUITABLE FOR INHIBITING PHOSPHOLIPASE A2 | PLD2, PLA2G1B, PLA2G4A | GAA 1064/4885HTT 4359/4885CNR2 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.